DMSC also implements STD/HIV intervention Programme among street-based sex workers and their clients, covering a population of over 20,000 sex workers and migrant laborers. DMSC currently implements and runs STD/HIV intervention programmes in 49 sex work sites in West Bengal.
The basic approach of Durbar's programme is pivoted on the principle of 3 Rs - Respect, Reliance and Recognition.

Respect towards sex workers,

Reliance on the knowledge and wisdom of the community of sex workers and,

Recognition of sex work as an occupation, for protecting their occupational and human rights.
Durbar is committed to the 3 Rs in all its activities and involves sex worker community in all decision-making and implementation. Durbar is active in building broader alliances to promote HIV prevention, care and support for HIV infected and affected individuals and families both at the national and regional levels.